Thank you Scott, appreciate the help.
I will probably go for the ASUS Crosshair VIII Hero instead of the ASUS® ROG STRIX X570-F because of the extra ports and minus the integrated GFX which has caused me headaches in the past.
Is there any particular reason you would stick with the STRIX motherboard?
The USB ports is a fair shout if you definitely think you will make good use of them. It's not as if the Strix is short of them haha.
The integrated GFX is disabled from scratch as the chips don't have iGPU processing.
The Crosshair is generally chosen for high end overclocking abilities and stable VRMs, etc, etc but it's an expensive premium for these features. Given the expense of this build I don't think there is any real need to quibble over £100 so you are probably right to go for it even just for peace of mind to know that you have the best available